Low Carb Pizza Casserole

Featured in family-meals.

Hey friend, you've got to try this pizza casserole! Imagine all your favorite pizza toppings – crispy pepperoni, savory mushrooms, and gooey melted cheese – layered over a golden cauliflower crust that's so good, you won't even miss the carbs. The photo shows that gorgeous bubbly cheese on top with those perfectly placed pepperoni slices getting all crispy around the edges. See how the mushrooms are caramelized to perfection? And that fresh basil scattered on top adds the perfect pop of color and flavor. This is comfort food that actually makes you feel good afterward. It comes together in one dish, bakes until golden and bubbly, and your whole kitchen will smell like an Italian pizzeria. Trust me, this is about to become your new weeknight hero!

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Updated on Sat, 15 Nov 2025 14:48:47 GMT
Main recipe image showcasing the final dish pin it
Cheesy low carb pizza casserole with pepperoni and mushrooms in white dish | lonerecipes.com

I'll never forget the first time I encountered a low-carb pizza alternative. I was at a friend's dinner party, and she served what looked like regular pizza but claimed it was keto-friendly. I was doubtful until I took that first bite – it was revelatory. That experience inspired me to create my own version at home. This Easy Low Carb Pizza Casserole takes everything I love about pizza and transforms it into a guilt-free casserole format. The base is made from cauliflower rice mixed with eggs and cheese, which creates a surprisingly firm and flavorful foundation. It's not trying to be pizza dough – it's something better in its own right. The layers build from there: a rich tomato sauce seasoned with Italian herbs, a generous blanket of melted mozzarella that gets all golden and bubbly, and then the toppings. I chose pepperoni for that classic pizza flavor and mushrooms for their meaty texture and earthy taste. The mushrooms caramelize as they bake, adding incredible depth. Fresh basil scattered on top brings brightness and a pop of color that makes it look as good as it tastes.

Why I love this recipe

I love this recipe because it proves that healthy eating doesn't have to be boring or restrictive. It delivers all the comfort and satisfaction of pizza night without the carb crash afterward. The cauliflower base is clever – it's filling and nutritious while letting the pizza flavors shine. What really wins me over is how versatile it is. Some nights I load it with vegetables, other times I keep it simple with just cheese and pepperoni. My family loves it, which means I can make one meal that makes everyone happy while still meeting my dietary goals. The fact that it all comes together in one casserole dish makes cleanup a breeze, and the leftovers actually taste better the next day once all the flavors have melded together. It's also incredibly forgiving – if you overbake it slightly, you just get extra crispy cheese edges, which is never a bad thing. This recipe has taught me that with a little creativity, you don't have to give up your favorite foods to eat well.

What You Need From Your Kitchen

  • Cauliflower rice: The low-carb base that replaces traditional pizza crust, providing texture and nutrition
  • Mozzarella cheese: Creates the gooey, melted cheese layer and binds the cauliflower crust together
  • Pizza sauce: Adds classic tomato flavor and moisture to the casserole
  • Pepperoni: Provides the iconic pizza taste and becomes crispy on top during baking
  • Mushrooms: Add meaty texture and earthy flavor while caramelizing in the oven
  • Eggs: Bind the cauliflower crust together and help it hold its shape

Let's Make These Together

Create the Cauliflower Crust Base
Start by preheating your oven and combining cauliflower rice with eggs, cheese, and seasonings in a large bowl. Mix everything together thoroughly so the cauliflower rice is completely coated. This mixture will form your sturdy, low-carb pizza crust that holds everything together beautifully. Press it firmly into your greased baking dish to create an even foundation layer.
Layer Your Pizza Flavors
Once your crust base is ready, spread a generous layer of pizza sauce over the top, making sure to cover the entire surface. Sprinkle the remaining mozzarella cheese evenly over the sauce, then add your mushroom slices and arrange the pepperoni on top. This layering technique ensures every bite has all those classic pizza flavors.
Bake Until Golden and Bubbly
Slide your assembled casserole into the preheated oven and let it bake until the cheese is completely melted and bubbling. You're looking for golden spots on the cheese and crispy edges on the pepperoni. The mushrooms should be caramelized and the whole dish should smell absolutely amazing. Let it rest for a few minutes before cutting to allow the layers to set properly.
Additional recipe photo showing texture and details pin it
Easy low carb pizza casserole with cauliflower crust and pepperoni slices | lonerecipes.com

Switch Things Up

I first made this casserole on a rainy Tuesday when I was craving pizza but didn't want to break my low-carb routine. I was skeptical about using cauliflower as a base, thinking it might be soggy or bland. But when I pulled it out of the oven and saw that golden, bubbly cheese with crispy pepperoni edges, I knew I'd found something special. The first bite completely changed my mind about cauliflower-based dishes. Now I make it at least twice a month, sometimes swapping the pepperoni for Italian sausage or adding bell peppers for extra vegetables. My kids actually request this over regular pizza, which still amazes me. It's become my go-to dish when I need something comforting but want to keep things healthy.

Perfect Pairings

This pizza casserole pairs beautifully with a crisp Caesar salad topped with Parmesan shavings and a tangy lemon dressing. For a heartier meal, serve it alongside some garlic butter roasted broccoli or zucchini noodles tossed in olive oil and herbs. A glass of dry red wine like Chianti or Sangiovese complements the tomato sauce and pepperoni perfectly. If you're feeding a crowd, add some mozzarella sticks or jalapeño poppers as appetizers, and finish with a light tiramisu or sugar-free cheesecake for dessert.

Step-by-step preparation photo pin it
Keto pizza casserole topped with melted mozzarella cheese and fresh basil | lonerecipes.com

Frequently Asked Questions

→ Can I use fresh cauliflower instead of cauliflower rice?

Yes! You can make your own cauliflower rice by pulsing fresh cauliflower florets in a food processor until they resemble rice grains. Just make sure to cook it briefly and squeeze out excess moisture before using it in the recipe to prevent a soggy crust.

→ Is this casserole freezer-friendly?

Absolutely! This casserole freezes beautifully. Let it cool completely, then wrap it tightly in plastic wrap and aluminum foil. It will keep in the freezer for up to 3 months. Thaw overnight in the refrigerator and reheat in a 350°F oven until warmed through.

→ Can I make this casserole ahead of time?

Yes, you can prepare the entire casserole up to 24 hours in advance. Assemble all the layers, cover tightly with plastic wrap, and refrigerate. When ready to bake, remove the plastic wrap and bake as directed, adding an extra 5-10 minutes to the baking time since it's starting cold.

→ What other toppings work well in this recipe?

This recipe is incredibly versatile! Try Italian sausage, ground beef, bell peppers, olives, onions, jalapeños, or spinach. You can also experiment with different cheeses like cheddar, provolone, or a Italian cheese blend for variety.

→ How do I prevent the cauliflower crust from being watery?

The key is removing excess moisture from the cauliflower rice. After cooking or thawing, place it in a clean kitchen towel or several layers of cheesecloth and squeeze firmly to remove as much liquid as possible. This step is crucial for a firm, non-soggy crust.

→ Can I make this recipe dairy-free?

While cheese is a main component, you can experiment with dairy-free mozzarella alternatives. However, the texture and flavor will differ from the original recipe. You may need to add extra binding agents to the cauliflower crust if using dairy-free cheese.

Conclusion

This Low Carb Pizza Casserole is proof that eating healthy doesn't mean sacrificing flavor. It's become a staple in my meal rotation because it satisfies those pizza cravings without derailing my goals. The cauliflower crust is surprisingly sturdy and flavorful, and the combination of cheese, pepperoni, and mushrooms creates that classic pizza taste we all love. Best of all, it's easy to customize with your favorite toppings and makes great leftovers for lunch the next day.

Low Carb Pizza Casserole

A delicious keto-friendly pizza casserole with all the flavors you love, minus the carbs. Perfect for weeknight dinners.

Prep Time
15 Minutes
Cook Time
30 Minutes
Total Time
45 Minutes
By: chris

Category: family-meals

Difficulty: easy

Cuisine: American

Yield: 6 Servings (6 balls)

Dietary: Low Carb, Keto, Gluten-Free

Ingredients

013 cups cauliflower rice
022 cups shredded mozzarella cheese
031 cup pizza sauce
0420 slices pepperoni
051 cup sliced mushrooms
062 large eggs
071 teaspoon Italian seasoning
081/2 teaspoon garlic powder
09Fresh basil for garnish

Instructions

Step 01

Preheat your oven to 375°F (190°C). In a large mixing bowl, combine the cauliflower rice, 1 cup of shredded mozzarella cheese, eggs, Italian seasoning, and garlic powder. Mix thoroughly until all ingredients are well incorporated and the cauliflower rice is evenly coated.

Step 02

Grease a 9x13 inch baking dish with cooking spray or butter. Press the cauliflower mixture firmly into the bottom of the dish, creating an even layer that covers the entire base. This will form your pizza crust foundation.

Step 03

Spread the pizza sauce evenly over the cauliflower crust layer. Sprinkle the remaining 1 cup of mozzarella cheese over the sauce. Distribute the sliced mushrooms evenly across the cheese layer, then arrange the pepperoni slices on top.

Step 04

Place the casserole in the preheated oven and bake for 25-30 minutes, or until the cheese is melted, bubbly, and slightly golden on top. The edges of the pepperoni should be crispy and the mushrooms caramelized.

Step 05

Remove the casserole from the oven and let it cool for 5 minutes to set. Garnish with fresh basil leaves torn or chopped. Cut into squares and serve hot. Enjoy your guilt-free pizza experience!

Notes

  1. For a crispier cauliflower crust, squeeze out excess moisture from the cauliflower rice using a clean kitchen towel or cheesecloth before mixing with other ingredients.
  2. You can substitute the pepperoni with Italian sausage, ground beef, or keep it vegetarian by adding more vegetables like bell peppers and olives.
  3. This casserole stores well in the refrigerator for up to 4 days. Reheat individual portions in the microwave or oven until warmed through.
  4. If you prefer a spicier version, add red pepper flakes to the cauliflower base or use spicy Italian sausage instead of pepperoni.
  5. Make sure to let the casserole cool for a few minutes before serving, as this helps it firm up and makes it easier to cut into portions.

Tools You'll Need

  • 9x13 inch baking dish
  • Large mixing bowl
  • Measuring cups and spoons
  • Wooden spoon or spatula
  • Cooking spray or butter
  • Sharp knife for slicing
  • Oven mitts

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Dairy (mozzarella cheese)
  • Eggs
  • Pork (pepperoni)

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 285
  • Total Fat: 19 g
  • Total Carbohydrate: 8 g
  • Protein: 22 g

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